Clinical Trial: Insulin Resistance in Idiopathic Oligospermia and Azoospermia
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: Insulin Resistance : a New Diagnosis of the Pathogenesis of Idiopathic Oligozoospermia and Non Obstructive Azoospermia
Brief Summary: Insulin resistance in men can be the underlying major factor in reproductive abnormalities ( chronic hypospermatogenesis ) as well as metabolic abnormalities similar to polycystic ovarian syndrome ( PCOS ) in women.
Detailed Summary: During the past decade IR has been recognized as a major contributor to the pathogenesis of chronic anovulation, hyperandrogenism and metabolic abnormalities associated with PCOS . Theoretically IR in men may result in a similar reproductive abnormalities ( chronic hypospermatogenesis ) as well as other metabolic abnormalities similar to what happens in PCOS in women .
Sponsor: The Egyptian IVF-ET Center
Current Primary Outcome: serum insulin [ Time Frame: one month ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Fasting Glucose [ Time Frame: one month ]
- cholesterol [ Time Frame: one month ]
- high density lipoprotein ( HDL) [ Time Frame: one month ]
- Low density lipoprotein ( LDL ) [ Time Frame: one month ]
- testosterone [ Time Frame: one month ]
- Triglycerides [ Time Frame: One month ]
Original Secondary Outcome:
- Glucose tolerance curve ( GTC ) [ Time Frame: one month ]
- cholesterol [ Time Frame: one month ]
- high density lipoprotein ( HDL) [ Time Frame: one month ]
- Low density lipoprotein ( LDL ) [ Time Frame: one month ]
- testosterone [ Time Frame: one month ]
Information By: The Egyptian IVF-ET Center
Dates:
Date Received: January 6, 2012
Date Started: January 2012
Date Completion:
Last Updated: November 23, 2014
Last Verified: November 2014
