Clinical Trial: Magnetocardiography as a Tool for Patients Presenting With Chest Pain - Pilot Study

Study Status: Completed
Recruit Status: Completed
Study Type: Observational

Official Title: Two Cohort, Pilot Study, to Identify Magnetocardiogram Characteristics That Can be Used to Classify Non Ischemic Chest Pain Patients and Myocardial Infarction Patients.

Brief Summary: The purpose of this pilot research study is to identify the characteristics of magnetocardiograms that correlate with a non ischemic chest pain status and a myocardial infarction patient status. The study uses a non SQUID magnetocardiogram device.

Detailed Summary:

Magnetocardiography (MCG) is a passive, non-contact technique to measure the electromagnetic activity of the heart.

Heart muscle is controlled by electrical impulses that initiate contraction of the myocardium to pump blood around the body. A wave of depolarisation and repolarisation helps to coordinate the heart's activity which is usually measured using an electrocardiogram (ECG) which reflects the surface electrical manifestation of myocardial depolarisation and repolarisation

For every electrical signal there is a corresponding magnetic field, as defined by Faraday's law of induction, and it is this magnetic field that MCG measures.

There are two key advantages of looking at the magnetic field rather than the electrical signal. (1) The signal is not attenuated as it passes through the body, so information is not lost and (2) changes in the action potential (for example those caused by ischemia) are 'magnified' in the magnetic field so are easier to detect by sensors that are not in direct contact with the body.

SQUID MCG has been used widely in cardiology research, and previous clinical studies have shown that the technology has potential for the analysis of patients with coronary artery disease.

The aim of this pilot study is to identify characteristics of MCG that differentiate patients with non-ischaemic chest pain from those with a myocardial infarction.


Sponsor: Quantum Imaging Limited

Current Primary Outcome: Magnetocardiogram Characteristics in patients with chest pain [ Time Frame: 1 hour ]

Quantitative comparison of magnetocardiogram characteristics of non ischaemic chest pain patients compared to those with an acute myocardial infarction


Original Primary Outcome: Same as current

Current Secondary Outcome: Device Safety [ Time Frame: At time of scan for all patiients (Varies) ]

Any adverse effects, adverse device effects, Unanticipated serious device effects


Original Secondary Outcome: Same as current

Information By: Quantum Imaging Limited

Dates:
Date Received: January 12, 2015
Date Started: February 2015
Date Completion:
Last Updated: August 3, 2015
Last Verified: February 2015