Clinical Trial: The Core Body Temperature Rhythms: Distinguishing MCS From UWS

Study Status: Completed
Recruit Status: Completed
Study Type: Observational [Patient Registry]

Official Title: The Core Body Temperature Rhythms:A Promising Indicator of Distinguishing MCS From UWS

Brief Summary: In this study, the core body temperature of 7 disorders of consciousness ( DOC ) patients were measured every 2 hour for 168 h .

Detailed Summary:

Living beings have multicomponent biological rhythms. There was a research recorded 24-h virations in electroencephalographic patterns. In normal subjects, the circadian rhythms of core body temperature is close to 24 h. When the interference of environmental and mental elements were eliminated, circadian rhythm shows the endogenous circadian rhythm of body acquiescently (>24h ), which is also called free-running period.

Measuring the continuous external auditory canal temperature of 4 unresponsive wakefulness syndrome (UWS) and 3 minimally conscious state(MCS) on the fluorescent lamp surrounding every 2 hours for 168 hours starting at 00:00 on the first day to address circadian capabilities.

Researchers expected to see the difference between MCS and UWS.


Sponsor: Jing Wang

Current Primary Outcome: Measuring the continuous external auditory canal temperature [ Time Frame: Continuous temperature measurements for 168 hours (8days) ]

VS patients have core body temperature periods which are longer than 24 hours; whereas MCS patients are shorter than 24 hours.


Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Hangzhou Normal University

Dates:
Date Received: September 29, 2016
Date Started: January 2015
Date Completion:
Last Updated: October 11, 2016
Last Verified: October 2016