Clinical Trial: Psychophysical Characterization and Brain Correlates of Dentine Hypersensitivity

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational

Official Title: Psychophysical Characterization and Brain Correlates of Dentine Hypersensitivity

Brief Summary: Up to date, devices capable of delivering controlled, calibrated, non-contact cold air stimuli in a MR environment are unavailable for quantitative sensory testing. This project therefore aimed at designing and constructing a novel MR-compatible, computer-controlled cold air stimulation device that produces air puffs in a broad flow and cold temperature range. By means of this device, detailed psychophysically testing and subsequent brain scanning of dentine hypersensitivity (DH) subjects will be possible to gain new insights about DH mechanisms.

Detailed Summary:
Sponsor: University of Zurich

Current Primary Outcome:

• Subjective ratings using the BORG scale [ Time Frame: May 1, 2016 ]
  individual subject perception ratings will be recorded by means of an adapted BORG scale. For reliability, intraclass correlations will be used covering 3-4 measures within a 3-4-weeks period.
• blood oxygenation level dependent (BOLD) response [ Time Frame: October 1, 2016 ]
  Changes in blood oxygenation level (indirect measure of neural activity) will be recorded

Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: University of Zurich

Dates:
Date Received: January 8, 2016
Date Started: July 2015
Date Completion: February 2017
Last Updated: October 7, 2016
Last Verified: October 2016