Clinical Trial: Developmental Coordination Disorder
Study Status: RECRUITING
Recruit Status: RECRUITING
Study Type: INTERVENTIONAL
Official Title: Developmental Coordination Disorder: Role of Perceptual Deficits and Body Representation
Brief Summary:
Developmental Coordination Disorder (DCD) corresponds to a clumsiness, a slowness and an inaccuracy of motor performance.
This neurodevelopmental disorder affects 6% of school-aged children, and disturbs daily life activities and academic performances.
The etiology of DCD is still unknown.
An understanding of this disorder is necessary to improve interventions and therefore quality of life of these people.
A deficit of the so-called internal models is the most commonly described hypothesis of DCD.
Indeed, children with DCD exhibit difficulties in predictive control.
Internal models, useful for motor control, are closely related to the sensory system, as they are elaborated on and constantly fed by sensory feedback.
Deficits in sensory performance are described in DCD, mostly in the visual system, which could in turn partly explain poor motor performance.
However, visuo-perceptual deficits cannot explain the entire motor difficulties because some activities in daily life, as buttoning a shirt, are often performed without visual control.
Although the integrity of proprioceptive and tactile systems is necessary for the building of internal models, and therefore for a stable motor control, these sensory systems have been very little investigated in DCD.
Moreover, using a tool is often disturbed in children with DCD.
In neurotypical subjects, tool use induces a plasticity of body representation, as reflected by modifications of movement kinematics after tool use.
Proprioceptive abilities are necessary for this update of the body schema.
Thus, potential deficits of the proprioceptive system in children with DCD could impair the plastic modification of the body schema, and hence of motor performance, when using a tool.
The aim of this study is to identify the main cause of the DCD, both by evaluating the tactile and proprioceptive abilities and by assessing the body schema updating abilities in children with DCD.
While some daily life activities improve with age, some motor difficulties persist in adults with DCD.
To our knowledge, perceptual abilities have never been investigated in adults with DCD and it is thus unknown whether perceptual deficits are still present in adulthood.
This information could allow us to understand if motor difficulties in adult DCD are caused by enduring perceptual deficits and/or impaired plasticity of body schema.
The second aim of this study is to evaluate abilities of perception and of body schema plasticity in adults with DCD.
Detailed Summary:
Sponsor: Hospices Civils de Lyon
Current Primary Outcome:
Difference in localization error distance between manual response and ocular response: measure in mm between the target and the response of the subject.
Task 1 : proprioceptive localization with manual response Task 2 : proprioceptive localization with ocular response Task 3: tactile localization with manual response Task 4: tactile localization with ocular response
In the 4 tests, we will measure the deviation (in mm) between the localization response of the subject and the reference point.
For tasks 1 and 2, the reference point is the position of the hidden index finger of the subject.
For tasks 3 and 4, the reference point is the position of the tactile stimulation applied to the hidden arm of the subject.
For the manual response, the subject must designate with his other index finger where he considers the target to be.
For the ocular saccadic response, the subject must shift his gaze and look where he considers the target to be.
Original Primary Outcome:
Difference in localization error distance between manual response and ocular response: measure in mm between the target and the response of the subject.
Task 1 : proprioceptive localization with manual response Task 2 : proprioceptive localization with ocular response Task 3: tactile localization with manual response Task 4: tactile localization with ocular response
In the 4 tests, we will measure the deviation (in mm) between the localization response of the subject and the reference point.
For tasks 1 and 2, the reference point is the position of the hidden index finger of the subject.
For tasks 3 and 4, the reference point is the position of the tactile stimulation applied to the hidden arm of the subject.
For the manual response, the subject must designate with his other index finger where he considers the target to be.
For the ocular saccadic response, the subject must shift his gaze and look where he considers the target to be.
Current Secondary Outcome:
Original Secondary Outcome:
Information By: Hospices Civils de Lyon
Dates:
Date Received: July 08, 2021
Date Started: December 21, 2021
Date Completion: January 21, 2024
Last Updated: January 30, 2023
Last Verified: January 01, 2023
