Clinical Trial: The Discovery of the Double Sphincter in Gallbladder

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title: The Discovery of the Double Sphincter in Gallbladder

Brief Summary: We found a new Double sphincter which located in the neck of gallbladder，we supposed it may be related to control pressure of bile duct.Its formation is related to genetic factors.

Detailed Summary: To contrast the recurrence rate of gallstones between patients with gallbladder double sphincter and patients with general gallbladder sphincter who underwent the treatment of cholecystolithiasis by minimally invasive cholecystolithotomy with gallbladder reservation. Method:Patients with gallbladder double sphincter and patients with general gallbladder sphincter who underwent the treatment of cholecystolithiasis by minimally invasive cholecystolithotomy with gallbladder reservation in The Affiliated Hospital of Guiyang Medical College from May 2012 to December 2015. We collect these patients' bile during surgery.Patients with gallbladder double sphincter as trial group, patients with general gallbladder sphincter as control group.the overall follow-up period is 3 years. Then the investigators statistically analyze improvement of cholecystolithiasis symptoms, thickness of gall bladder wall, the gallbladder function and the rate of the recurrence of cholesterol gallstone in 2 groups.we also analysis of the genetic differences from bile between two groups.
Sponsor: The First Affiliated Hospital of Guangzhou Medical University

Current Primary Outcome: The Discovery of The Double Sphincter in Gallbladder [ Time Frame: All the patients will be follow-up for an expected average of 3 years. ]

The gallbladder of some gallstone patients contain a new Anatomical structure named Double sphincter which located in the middle of gallbladder，we supposed it may be related to the formation of gallstone and pressure of bile duct.Its formation is related to genetic factors.


Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: The First Affiliated Hospital of Guangzhou Medical University

Dates:
Date Received: November 13, 2013
Date Started: December 2012
Date Completion: December 2018
Last Updated: March 6, 2016
Last Verified: March 2016