Clinical Trial: Use of Ketamine Prior to Cardiopulmonary Bypass in Children
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: Use of Ketamine Prior to Cardiopulmonary Bypass in Children
Brief Summary: To assess whether the drug ketamine given prior to cardiopulmonary bypass can decrease injury to the cells in the brain.
Detailed Summary:
Sponsor: Arkansas Children's Hospital Research Institute
Current Primary Outcome:
- To compare expression of serum markers of CNS injury [ Time Frame: within 48 hours ]
- to compare expression of multiple pro and anti-inflammatory cytokines between cases and controls. [ Time Frame: within 48 hours ]
Original Primary Outcome: Same as current
Current Secondary Outcome: to compare the clinical, radiological and neurodevelopmental outcomes of the cases and controls [ Time Frame: one month ]
Original Secondary Outcome: Same as current
Information By: Arkansas Children's Hospital Research Institute
Dates:
Date Received: November 9, 2007
Date Started: July 2004
Date Completion:
Last Updated: November 9, 2007
Last Verified: November 2007
