Clinical Trial: Localization of Parathyroid Adenoma by Fluorocholine PET/MRI (Positron Emission Tomography -MRI)

Study Status: Not yet recruiting
Recruit Status: Not yet recruiting
Study Type: Interventional

Official Title: Localization of Parathyroid Adenoma by Fluorocholine Positron Emission Tomography/MRI (PET/MRI): A Prospective Pilot Study

Brief Summary: A comparative prospective study to evaluate different imaging modalities (pet-ct and pet-mr) prior to surgery in parathyroid tumor patients.

Detailed Summary: Patients with Hyperthyroidism and surgery indication will be recruited and directed to imagine exams. in addition to the conservative 99mTc-MIBI (methoxyisobutylisonitrile) and US, patients will also undergo 18FCH (¹⁸F-choline) PET/MRI for detecting adenomas and their location. imaging experts will decode the imaging exams. sensitivity and specificity of the exams will be examined.
Sponsor: Assuta Medical Center

Current Primary Outcome: Adenomas size and location [ Time Frame: 24 months ]

Location of adenomas by a report analyzing the pathological examination (PET-CT/PET-MR output).


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Parathyroid hormone levels [ Time Frame: 24 months ]
    approval late addition level of parathyroid hormone (PTH) before and during the course of the operation after the conclusion of adenomas (Hormone levels).
  • Chronic disease duration [ Time Frame: 24 months ]
    time from chronic diseases indication and duration of symptoms measured in months (from the medical records).
  • Disease related medication consumption [ Time Frame: 24 months ]
    Disease related medication consumption measured in miligram (mg) for each medication (from medical records).


Original Secondary Outcome: Same as current

Information By: Assuta Medical Center

Dates:
Date Received: July 14, 2016
Date Started: August 2016
Date Completion: December 2018
Last Updated: July 21, 2016
Last Verified: July 2016