Clinical Trial: Effects of Cord Blood 25-hydroxy-vitamin D Level on Early Neonatal Morbidities

Study Status: Completed
Recruit Status: Completed
Study Type: Observational

Official Title:

Brief Summary: Cholecalciferol (vitamin D3) is a prohormone and its active form is 1,25 dihydroxycholecalciferol. This hormone has effect on both calcium, phosphorus and bone metabolism and also bone morrow, muscle, heart and immune system. For a long time, maternal low vitamin D level is a well known problem for our country and the level was reported as <10 ng/ml for 46-80% of mothers.The most prominent risk factor was determined as low socioeconomic status. Therefore, the level of 25-hydroxy-vitamin D is supposed to be in relation with several neonatal morbidities and maternal complications of pregnancy.

Detailed Summary:
Sponsor: Zekai Tahir Burak Women's Health Research and Education Hospital

Current Primary Outcome:

  • sepsis [ Time Frame: 3 months but patients will be followed until discharge ]
  • feeding intolerance [ Time Frame: 3 months but patients will be followed until discharge ]
  • hypocalcemia [ Time Frame: 3 months but patients will be followed until discharge ]
  • bronchopulmonary dysplasia [ Time Frame: 3 months but patients will be followed until discharge ]
  • patent ductus arteriosis [ Time Frame: 3 months but patients will be followed until discharge ]
  • retinopathy of prematurity [ Time Frame: 3 months but patients will be followed until discharge ]
  • maternal complications of pregnancy [ Time Frame: from the beginning of gestation until birth process ]


Original Primary Outcome:

  • sepsis [ Time Frame: 3 months but patients will be followed until discharge ]
  • feeding intolerance [ Time Frame: 3 months but patients will be followed until discharge ]
  • hypocalcemia [ Time Frame: 3 months but patients will be followed until discharge ]
  • bronchopulmonary dysplasia [ Time Frame: 3 months but patients will be followed until discharge ]
  • patent ductus arteriosis [ Time Frame: 3 months but patients will be followed until discharge ]
  • retinopathy of prematurity [ Time Frame: 3 months but patients will be followed until discharge ]
  • maternal complications of pregnancy [ Time Frame: at birth ]


Current Secondary Outcome: rachitism [ Time Frame: 4 months but patients will be followed until discharge ]

Original Secondary Outcome: Same as current

Information By: Zekai Tahir Burak Women's Health Research and Education Hospital

Dates:
Date Received: May 21, 2014
Date Started: October 2013
Date Completion:
Last Updated: May 27, 2014
Last Verified: May 2014