Clinical Trial: Variations in Retinal Nerve Fiber Layer Thickness During Uncomplicated Anterior and Intermediate Uveitis

Study Status: Not yet recruiting
Recruit Status: Not yet recruiting
Study Type: Observational

Official Title: Variations in Retinal Nerve Fiber Layer Thickness During Uncomplicated Anterior and Intermediate Uveitis

Brief Summary: This study investigates the variations in the retinal nerve fiber layer (RNFL) thickness during uncomplicated anterior and intermediate uveitis, respectively. The objectives are to 1 ) confirm the RNFL thickening during an uncomplicated anterior uveitis as described in the literature, 2) measure the RNFL thickness during an uncomplicated intermediate uveitis specifically and 3) describe the variation in time of RNFL thickness during the two types of uveitis.

Detailed Summary: Thirty six individuals (18 with anterior uveitis and 18 with intermediate uveitis) will be recruited at the Centre universitaire d'ophtalmologie du CHU de Québec. RNFL thickness will be measured with optical coherence tomography at 3 times. For anterior uveitis, the RNFL thickness will be measured at presentation, 1 week and 4 to 6 weeks. For intermediate uveitis, the RNFL thickness will be measured at presentation, 4 to 6 weeks and 4 months. The initial thickness will be studied for each type of uveitis and progression over time will be studied also for each type of uveitis.
Sponsor: Centre Hospitalier Universitaire de Québec, CHU de Québec

Current Primary Outcome:

  • Retinal Nerve Fiber Layer Thickness in anterior uveitis [ Time Frame: At time 0 ]
  • Retinal Nerve Fiber Layer Thickness in intermediate uveitis [ Time Frame: At time 0 ]
  • Change from Baseline Retinal Nerve Fiber Layer Thickness in anterior uveitis [ Time Frame: at 4 to 6 weeks ]
  • Change from Baseline Retinal Nerve Fiber Layer Thickness in intermediate uveitis [ Time Frame: at 4 months ]


Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Centre Hospitalier Universitaire de Québec, CHU de Québec

Dates:
Date Received: August 4, 2016
Date Started: September 2016
Date Completion: March 2018
Last Updated: August 22, 2016
Last Verified: August 2016