Clinical Trial: Corneal Cross Linking and Topography Guided Excimer Laser Treatment
Study Status: Terminated
Recruit Status: Terminated
Study Type: Interventional
Official Title: Topography Guided Excimer Laser Surface Ablation in Combination With Corneal Cross-linking (CCL) in Patients With Progressive Ectatic Corneal Disorders.
Brief Summary:
Topography guided laser treatment enables the surgeon to correct higher order aberrations in corneas with irregular astigmatism. Several case reports and small uncontrolled trials have been published on the combination of this treatment with corneal cross linking (CCL) in patients with ectatic corneal diseases.
This randomized study will evaluate the safety and efficacy of a combined treatment of corneal cross linking with a partial topography guided excimer laser treatment in eyes with progressive ectatic corneal diseases.
Detailed Summary:
Sponsor: Medical University of Vienna
Current Primary Outcome:
- Safety (Pachymetry, K-readings) [ Time Frame: 1 year ]
- uncorrected visual acuity (UVCA) [ Time Frame: 1 year ]
- best corrected visual acuity (BCVA) [ Time Frame: 1 year ]
Original Primary Outcome: Same as current
Current Secondary Outcome: Progression of ectatic disease (by use of maximum keratometry readings = Kmax) [ Time Frame: 1 year ]
Original Secondary Outcome: Same as current
Information By: Medical University of Vienna
Dates:
Date Received: November 5, 2011
Date Started: January 2010
Date Completion:
Last Updated: April 25, 2017
Last Verified: April 2017
