Clinical Trial: Hormonal Status on Blood Flow and Tissue in Pelvic Organ Prolapse
Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional
Official Title: Role of Hormonal Status on Vascularization and Vaginal Tissue in Women With Pelvic Organ Prolapse
Brief Summary: Our primary aim in the current study is to determine important tissue differences, including muscle and connective tissue changes, between postmenopausal women and reproductive age women with pelvic floor dysfunction to help develop targeted and noninvasive treatments.
Detailed Summary:
Sponsor: The University of Texas Medical Branch, Galveston
Current Primary Outcome: Composite of vaginal wall inflammatory markers and macrocirculatory and microcirculatory flow on pelvic floor dysfunction [ Time Frame: 1-month perioperative study ]
Original Primary Outcome: Same as current
Current Secondary Outcome: Composite of tissue matrix metalloproteinases, collagen/elastin structure, microvasculature and muscle thickness [ Time Frame: 1-month perioperative study ]
Original Secondary Outcome: Same as current
Information By: The University of Texas Medical Branch, Galveston
Dates:
Date Received: June 14, 2013
Date Started: June 2013
Date Completion: December 2018
Last Updated: May 1, 2017
Last Verified: December 2016