Clinical Trial: Periodontal Disease Treatment of a Physically Challenged Population

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: The Effect of an Antibiotic-antifungal Rinse on Periodontal Disease

Brief Summary:

Many physically handicapped patients at the dental department, Toronto Rehabilitation Institute(TRI) have considerable gingival inflammation and breath odour because of the inability to effectively handle a toothbrush. These patients have considerable periodontal disease. There is a concern that these pathogens may have a detrimental effect on wound healing in other areas of the body.

Hypothesis: Patients attending the dental department at TRI that are treated with the antibiotic-antifungal rinse containing metronidazole and nystatin will show substantial decrease in periodontal disease as measured by bleeding points and pocket depth when compared to the group that continues to use their regular oral hygiene methods (control group).

Detailed Summary:
Sponsor: Oravital Inc

Current Primary Outcome: Evidence of healing of periodontal tissues as shown by a reduction of bleeding [ Time Frame: two weeks ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Oravital Inc

Dates:
Date Received: October 29, 2012
Date Started: November 2013
Date Completion:
Last Updated: March 29, 2016
Last Verified: March 2016