Clinical Trial: Immunoregulation of Periodontal Disease
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: Immunoregulation of Periodontal Disease
Brief Summary: Our design is to test in hospital practice a selection of immune parameters that could assess the pathophysiology and progression of periodontal lesions.
Detailed Summary: These parameters will be measured in 25 healthy volunteers and 25 moderate-to severe periodontal disese patients. Phagocytes will be tested phenotypically and functionally, both ex vivo and in vitro.
Sponsor: Assistance Publique Hopitaux De Marseille
Current Primary Outcome: Percentage of positive cells and intensity of expression for the molecules of surface studied there cytometric in stream [ Time Frame: 24 months ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Rate of secretion of cytokines and the other substances [ Time Frame: 24 months ]
- Detection and quantification of ARN messengers [ Time Frame: 24 months ]
Original Secondary Outcome: Same as current
Information By: Assistance Publique Hopitaux De Marseille
Dates:
Date Received: June 18, 2008
Date Started: August 2008
Date Completion:
Last Updated: August 27, 2014
Last Verified: August 2014
