Clinical Trial: Penicillin and Metronidazole in Treatment of Peritonsillar Abscess

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Penicillin and Metronidazole in Treatment of Peritonsillar Abscess - Prospective, Double-blind, Randomized, Placebo-controlled Study

Brief Summary: Treatment of peritonsillar abscess varies. To study whether broad spectrum antibiotics are required in addition to abscess drainage we perform a prospective, double blind, placebo-controlled, randomised study on 200 adult patients with peritonsillar abscess. 100 patients are given penicillin and metronidazole and 100 patients get penicillin and placebo. Recovery and recurrence and analyzed.

Detailed Summary:
Sponsor: Helsinki University Central Hospital

Current Primary Outcome: Efficacy of metronidazole in addition to penicillin in preventing the recurrence of peritonsillar abscess [ Time Frame: 60 days ]

Original Primary Outcome: Same as current

Current Secondary Outcome: Does metronidazole in addition to penicillin enhance the recovery of peritonsillar abscess [ Time Frame: 30 days ]

Original Secondary Outcome: Same as current

Information By: Helsinki University Central Hospital

Dates:
Date Received: December 6, 2010
Date Started: February 2010
Date Completion:
Last Updated: April 8, 2011
Last Verified: December 2010