Clinical Trial: Long-term Effects of Transcranial Direct Current Stimulation (tDCS) on Patients With Phantom Limb Pain (PLP)

Study Status: Suspended
Recruit Status: Suspended
Study Type: Interventional

Official Title: Long-Term Treatment of Patients Experiencing Phantom Limb Pain With Transcranial Direct Current Stimulation (tDCS)

Brief Summary:

  • Phantom limb pain (PLP) refers to pain in a limb that has been amputated or deafferented. Phantom limb pain might be related to brain cortical plastic changes.
  • The purpose of this study is to determine the efficacy of a series of transcranial direct current stimulation (tDCS) sessions, a non-invasive and focal brain stimulation method, in producing long-term reduction of phantom limb pain among amputees who experience such pain.

This is a Crossover sham control.


Detailed Summary:
Sponsor: Sheba Medical Center

Current Primary Outcome: Reduced phantom limb pain [ Time Frame: 5 months after last stimulation session ]

Reduction of phantom limb pain compared to phantom limb pain before treatment, according to Visual Analog Scales (VAS) evaluation


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Adverse effects of treatment [ Time Frame: Up to 5 weeks ]
    Severity of any adverse effects related to the transcranial direct current stimulation treatment will be checked after each stimulation session
  • Effects of treatment on the electrical activity of the brain [ Time Frame: Up to 5 weeks ]
    Measurement of the electrical activity of the brain before, during and after each stimulation using an electroencephalography (EEG) device.


Original Secondary Outcome: Same as current

Information By: Sheba Medical Center

Dates:
Date Received: January 28, 2014
Date Started: May 2015
Date Completion: December 2017
Last Updated: January 26, 2016
Last Verified: January 2016