Clinical Trial: Intraumbilical Misoprostol in Retained Placenta

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Intra-umbilical Injection of Misoprostol Versus Normal Saline in the Management of Retained Placenta: Intrapartum Placebo-controlled Trial

Brief Summary: Administration of intraumbilical misoprostol to women with retained placenta despite active management of third stage of labour reduces the need for manual removal of placenta and the amount of blood loss vaginally.

Detailed Summary: Retained placenta (RP)is one of the complications of third stage of labour; it should be managed promptly as it may cause severe bleeding, infection, maternal morbidity and mortality .The current standard management of RP word wide, by manual removal aims to prevent these problems, but it is unsatisfactory method because it requires general anaesthesia in hospital, It is an invasive procedure with its own serious complications of bleeding, infection and genital tract injury. Umbilical vein injection of misoprostol is a simple, safe method and could be performed at the place of delivery .
Sponsor: Hawler Medical University

Current Primary Outcome: delivery of placenta by medical intervention [ Time Frame: 30 minutes after the injection of misoprostol or normal saline in the umbilical vein ]

The administration of intraumbilical misoprostol to women with retained placenta despite active management of third stage of labour reduces the need for manual removal of placenta under general anaesthesia.


Original Primary Outcome: Same as current

Current Secondary Outcome: vaginal bleeding after misoprostol use [ Time Frame: 30 minutes after umbilical vein injection of misoprostol ]

using intraumbilical misoprostol in women with retained placenta reduces the amount of blood loss vaginally.


Original Secondary Outcome: Same as current

Information By: Hawler Medical University

Dates:
Date Received: April 18, 2013
Date Started: April 2011
Date Completion:
Last Updated: November 1, 2013
Last Verified: November 2013