Clinical Trial: Diagnosis of Macrophage Coronary Plaque by Optical Tomographic Imaging

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational

Official Title: Diagnosis of Macrophage Coronary Plaque by Optical Tomographic Imaging : A Comparative Study With Coronary Artery of the Transplanted or Autopsy Heart

Brief Summary: This study evaluated optimal macrophage diagnosis algorithm through comparative analysis between coronary artery, OCT image, and IVUS, and improve a diagnosis rate of vulnerable coronary plaque accompanied with macrophage infiltration.

Detailed Summary:
Sponsor: Young-Hak Kim, MD, PhD

Current Primary Outcome: ROC curve of diagnosis [ Time Frame: within 48 hours ]

Receiver Operating Characteristic curve of diagnosis through existing NSD(normalized standard deviation)-based method and developed algorithm in the diagnosis of coronary plaque accompanied with macrophage infiltration


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • fibrin accumulation [ Time Frame: within 48 hours ]
  • neoatherosclerosis [ Time Frame: within 48 hours ]
  • elastic lamia [ Time Frame: within 48 hours ]
  • cholesterol crystal [ Time Frame: within 48 hours ]
  • microcalcification [ Time Frame: within 48 hours ]


Original Secondary Outcome: Same as current

Information By: Asan Medical Center

Dates:
Date Received: January 6, 2016
Date Started: May 2015
Date Completion: March 2019
Last Updated: July 13, 2016
Last Verified: July 2016