Clinical Trial: A Quality of Life Study re Management of Malignant Pleural Effusions
Study Status: Completed
Recruit Status: Completed
Study Type: Observational
Official Title: A Prospective Study of Patient Centered Outcomes in the Management of Malignant Pleural Effusions
Brief Summary: There is much data in the literature regarding optimal treatment approaches for malignant pleural effusions as assessed by patient outcomes. However, data on quality of life and satisfaction with treatment from the patient's perspective is not available.
Detailed Summary:
This study will compare various treatment strategies in the management of malignant pleural effusions with respect to:
- Primary endpoint: the successful palliation of symptomatic pleural effusions as assessed by the London Chest Activity of Daily Living Scale (LCADLS)
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Secondary endpoints:
i) impact of treatment on patient quality of life as assessed by the Functional Assessment of Chronic Illness Therapy - Palliative patient (FACIT-PAL) questionnaire ii) Assessment of patient satisfaction with treatment received via Functional Assessment of Chronic Illness Therapy-Treatment Satisfaction (FACIT-TS) questionnaire iii)Pleurodesis success rates assessed by 2 and 6-week effusion control rates on CXR iv) Requirement of further hospitalizations or procedures for the treatment of recurrent effusions v) Comparison of morbidity and mortality rates for differing treatment approaches vi) comparison of cost in a Canadian health care setting for differing treatment approaches
Sponsor: University Health Network, Toronto
Current Primary Outcome: the successful palliation of symptomatic pleural effusions as assessed by the London Chest Activity of Daily Living Scale (LCADLS) [ Time Frame: discharge, 2 wks and 6 wks ]
Original Primary Outcome:
Current Secondary Outcome:
Original Secondary Outcome:
Information By: University Health Network, Toronto
Dates:
Date Received: September 12, 2005
Date Started: August 2004
Date Completion:
Last Updated: May 3, 2017
Last Verified: May 2017
