Clinical Trial: The Effect of Rosuvastatin in Diabetic Polyneuropathy: A Phase IIa Randomized Double-blind Placebo-controlled Study
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: Phase IIa Randomized Double-blind Placebo-controlled Study to Evaluate the Effect of Rosuvastatin in Diabetic Polyneuropathy
Brief Summary: To evaluate the impact of oral rosuvastatin in diabetic polyneuropathy, and the role of lipid peroxidation and nerve growth factor.
Detailed Summary:
Sponsor: Alejandra Guillermina Miranda Diaz
Current Primary Outcome:
- Stage of diabetic polyneuropathy [ Time Frame: 12 weeks ]
- Severity of diabetic polyneuropathy [ Time Frame: 12 weeks ]Severity according nerve conduction studies
- Nerve conduction studies [ Time Frame: 12 weeks ]
- Neuropathy symptoms and impairment scores [ Time Frame: 12 weeks ]
- Lipid peroxidation [ Time Frame: 12 weeks ]
- Nerve growth factor [ Time Frame: 12 weeks ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
Original Secondary Outcome:
Information By: University of Guadalajara
Dates:
Date Received: June 15, 2012
Date Started: February 2010
Date Completion:
Last Updated: June 18, 2012
Last Verified: June 2012
