Clinical Trial: Misoprostol Versus Oxytocin for Prevention of Post Partum Hemorrhage

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Safety and Efficacy of Misoprostol Versus Oxytocin for Prevention of Post Partum Hemorrhage

Brief Summary: Post partum Hemorrhage (PPH) is one of three main causes of death in pregnant women. Oxytocin is widely used for prevention of PPH. Some studies suggested misoprostol as an alternative treatment when Oxytocin isn't available. The aim of this study is to compare the safety and efficacy of Oxytocin and misoprostol for prevention of PPH.

Detailed Summary: In a double blind randomized controlled trial 400 pregnant women who has vaginal delivery at Shariati hospital are assigned into two groups either to receive 20 unite oxytocin in 1000cc ringer and 2 placebo tablet or 400mcg oral misoprostol and 2cc normal saline in 1000cc ringer.
Sponsor: Hormozgan University of Medical Sciences

Current Primary Outcome: Amount of bleeding [ Time Frame: 1 hour ]

within 1 hours after delivery


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Hemoglobin decrease [ Time Frame: 24 hours ]
  • Hematocrite decrease [ Time Frame: 24 hours ]


Original Secondary Outcome: Same as current

Information By: Hormozgan University of Medical Sciences

Dates:
Date Received: May 23, 2013
Date Started: May 2013
Date Completion:
Last Updated: March 25, 2015
Last Verified: March 2015