Clinical Trial: Physical Exercise and Ketone Production in Women With or Without Prediabetes
Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional
Official Title: Stimulating the Production of Ketones Through the Combined Use of Physical Exercise and Dietary a Medium Chain Triglycerides (MCT) Supplement
Brief Summary: The aim of this study is to compare the effect on ketone production of dietary an MCT supplement combined or not with physical exercise in two groups of women (N=10/group), healthy adults and patients with prediabetes. After an evaluation of the metabolism (a 4-hour visit with multiple blood samples) at the beginning of the study, all the participants are taken for one-week the MCT supplement alone follow by a one-week period of taking the MCT supplement in combination with physical exercise. At the end of each period of time, the 4-hour visit for the evaluation of the metabolism is repeated.
Detailed Summary:
Sponsor: Université de Sherbrooke
Current Primary Outcome: Plasma ketone concentrations [ Time Frame: 5 days ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Plasma glucose concentrations [ Time Frame: 5 days ]Glucose (mM)
- Plasma cholesterol concentrations [ Time Frame: 5 days ]Total cholesterol (mM)
- Plasma triglyceride concentrations [ Time Frame: 5 days ]Triglycerides (mM)
- Plasma free fatty acid concentrations [ Time Frame: 5 days ]Free fatty acids (mM)
- Plasma insulin concentrations [ Time Frame: 5 days ]Insulin (IU/L)
Original Secondary Outcome: Same as current
Information By: Université de Sherbrooke
Dates:
Date Received: February 5, 2016
Date Started: September 2015
Date Completion: March 2018
Last Updated: March 27, 2017
Last Verified: May 2016