Clinical Trial: Two-Dose Methotrexate for Ectopic Pregnancy

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Two-Dose Methotrexate for Ectopic Pregnancy

Brief Summary: This study examines the safety and acceptability of a novel "two dose" regimen of methotrexate to treat ectopic pregnancy.

Detailed Summary: The regimen is an attempt to create a middle ground between the 2 commonly used regimens - "single dose" and "multi dose". The "multi dose" regimen is more effective, but the "single dose" regimen is more convenient for patients and has fewer side effects.
Sponsor: University of Pennsylvania

Current Primary Outcome: Prevalence of side effects [ Time Frame: Till quantitative bhCG values fall to zero or below 5mIU/mL ]

Original Primary Outcome: Prevalence of side effects

Current Secondary Outcome: Efficacy of treatment of ectopic pregnancy (defined as no surgical intervention) [ Time Frame: Till quantitative bhCG values fall to zero or below 5mIU/mL ]

Original Secondary Outcome: Efficacy of treatment of ectopic pregnancy (defined as no surgical intervention)

Information By: University of Pennsylvania

Dates:
Date Received: September 13, 2005
Date Started: March 2001
Date Completion:
Last Updated: August 8, 2011
Last Verified: August 2011