Clinical Trial: Evaluation of Therapeutic Strategies for Treatment of Ectopic Pregnancies (EP) and Evaluation of Subsequent Fertility
Study Status: Completed
Recruit Status: Unknown status
Study Type: Interventional
Official Title: Prospective Study, Randomized Controlled Trial Between Medical Treatment by Methotrexate Versus Conservative Surgical Treatment (Group 1) and Conservative Versus Radical Surgical Treatment (Group 2) t
Brief Summary: Three protocols are used to treat ectopic pregnancies: medical treatment by methotrexate, conservative surgery or radical surgery. There are no data about subsequent fertility except in a cohort study. The investigators propose to evaluate the true subsequent fertility with a follow-up of 2 years, in a randomized controlled trial.
Detailed Summary: The first group includes non active ectopic pregnancies defined by score or algorithm. In this case, we propose a randomized controlled trial between medical and conservative surgery. In all others clinical situations, we proposed surgery treatment. In a randomized controlled trial we compare conservative versus radical treatment. The patients are followed-up during 2 years with phone contact every 6 months.
Sponsor: Hopital Antoine Beclere
Current Primary Outcome: Subsequent fertility with 2 years follow-up
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Complications of treatments
- Time of hospitalisation
- Decrease curve of beta-hCG after treatment
- Success rate in each group
Original Secondary Outcome: Same as current
Information By: Hopital Antoine Beclere
Dates:
Date Received: August 29, 2005
Date Started: August 2004
Date Completion: July 2008
Last Updated: September 7, 2006
Last Verified: August 2005
