Clinical Trial: Genetic Epidemiology of Primary Biliary Cirrhosis (PBC)
Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational
Official Title: Understanding the Genetic Predisposition to the Development of Primary Biliary Cirrhosis (PBC).
Brief Summary:
Primary Biliary Cirrhosis (PBC) is a progressive liver disorder of unknown cause. Current evidence suggests that genes, the genetic material we inherit from our parents, in combination with environmental factors, likely play an important role in the development of PBC.
This study is being done to investigate whether genes make people more likely to develop PBC. Discovery of these proposed genes will help us better understand how PBC developes, and subsequently, to apply new approaches for its prevention, diagnosis and treatment.
Detailed Summary:
Sponsor: Mayo Clinic
Current Primary Outcome: Mapping of Susceptibility Genes in Adult Chronic Cholestatic Liver Diseases
Adult chronic cholestatic liver diseases, such as Primary Biliary Cirrhosis (PBC), are progressive liver disorders of unknown cause. Current evidence suggests that genes, the genetic material we inherit from our parents, in combination with environmental factors, likely play an important role in the development of PBC.
This study is being done to investigate whether genes (the inherited genetic material passed from parents to their children) make people more likely to develop PBC. Discovery of these proposed genes will help us to better understand how PBC progresses, and subsequently, to apply new approaches for its prevention, diagnosis and treatment.
Original Primary Outcome:
Current Secondary Outcome:
Original Secondary Outcome:
Information By: Mayo Clinic
Dates:
Date Received: July 12, 2010
Date Started: March 2002
Date Completion: December 2025
Last Updated: April 12, 2016
Last Verified: April 2016
