Clinical Trial: Magnetic Resonance Imaging (MRI) Solely For Liver Stereotactic Body Radiation Therapy (SBRT)
Study Status: Completed
Recruit Status: Completed
Study Type: Observational
Official Title: Magnetic Resonance Imaging (MRI) Solely For Liver Stereotactic Body Radiation Therapy (SBRT)
Brief Summary: This study is a research and development initiative established to explore the use of magnetic resonance imaging (MRI) as a tool for managing organ motion of the liver in cancer patients planning procedures for stereotactic body radiation therapy (SBRT).
Detailed Summary: There is a potential role to systematically implement MRI to establish appropriate workflow of the implementation for tumor motion management in liver SBRT. Compared to CT, MRI has many significant advantages for radiotherapy planning, including superior tumor and soft-tissue contrast, flexible imaging orientation, freedom from radiation exposure and real-time imaging. MRI solely based liver SBRT will allow for more precise delineation of target volume, less uncertainties in treatment planning, better motion management, and potentially better treatment outcome
Sponsor: Duke University
Current Primary Outcome:
- Measure average motion trajectories [ Time Frame: During MRI approx 1 hour ]
- Image quality, as measured by image rating [ Time Frame: During MRI approx 1 hour ]Image quality will be measured on a scale of 1 to 5, 1 being the best.
- Image quality, as measured by tumor volume [ Time Frame: During MRI approx 1 hour ]
- Image quality, as measured by tumor-to-live contrast to noise ratio [ Time Frame: During MRI approx 1 hour ]
- Planning target volume (PTV) [ Time Frame: During MRI approx 1 hour ]PTV is defined as PTV=internal target volume (ITV) + safety margin (M)
Original Primary Outcome: Same as current
Current Secondary Outcome:
Original Secondary Outcome:
Information By: Duke University
Dates:
Date Received: March 14, 2016
Date Started: August 2016
Date Completion:
Last Updated: April 5, 2017
Last Verified: April 2017
