Clinical Trial: Effects of Coenzyme Q10 in Progressive Supranuclear Palsy (PSP)
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: Effects of Coenzyme Q10 in Progressive Supranuclear Palsy (PSP): A Multicenter, Randomized, Placebo-controlled, Double Blind Study
Brief Summary: The clinical syndrome of PSP responds poorly to all available forms of therapy used in Parkinson's Disease (PD). Currently, no effective treatment exists. Coenzyme Q10 in high doses has been shown to be a beneficial therapy in PD and might possibly be a beneficial therapy for PSP. This study will compare the efficacy, safety and tolerability of Coenzyme Q10 versus placebo in patients with atypical parkinsonian syndrome, progressive supranuclear palsy (PSP).
Detailed Summary: The study is designed as a multicenter randomized, placebo-controlled, double blind trial. Up to 60 patients with PSP will be enrolled at several centers in the United States
Sponsor: Lahey Clinic
Current Primary Outcome:
- Rate of Functional decline [ Time Frame: 12 months ]
- Functional ability [ Time Frame: 12 months ]
Original Primary Outcome:
- Rate of Functional decline
- Functional ability
Current Secondary Outcome:
- Safety [ Time Frame: 12 months ]
- Quality of Life [ Time Frame: 12 months ]
Original Secondary Outcome:
- Safety
- Quality of Life
Information By: Lahey Clinic
Dates:
Date Received: September 28, 2006
Date Started: September 2006
Date Completion:
Last Updated: August 4, 2015
Last Verified: August 2015
