Clinical Trial: Evaluation of the Effectiveness of a Protein Pulse-Feeding Pattern in Elderly Patients

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Evaluation of the Effectiveness of a Protein Pulse-Feeding Pattern in Elderly Patients

Brief Summary: The researchers tested the hypothesis that a protein pulse-feeding pattern was more efficient in improving muscle mass and immune functions than was a protein spread-feeding pattern, after 45 days, in elderly malnourished patients.

Detailed Summary:

To estimate the amelioration of the accretion in protein and the immunizing deficit thanks to a nutrition "PULSEE" ( to hold on 80 % of the proteic by day in on meal) with a proteic distributed all along the day for old subjects having a denutrition

To also estimate that the diminution of the morbidity decrease (infections, bedsores) the average during the stay and the mortality according to 2 modalities of grip nutritional


Sponsor: Assistance Publique - Hôpitaux de Paris

Current Primary Outcome: Lean mass (dual energy X-ray absorptiometry [DEXA] and bioelectrical-impedance analysis [BIA]) [ Time Frame: 42 days ]

Original Primary Outcome: Lean mass (DEXA and BIA) at 42 days

Current Secondary Outcome:

  • Immune functions [ Time Frame: 42 days ]
  • Hand-grip strength [ Time Frame: 42 days ]
  • Biological nutritional parameters [ Time Frame: 42 days ]
  • Mortality and morbidity (infections and bedsores) [ Time Frame: 42 days ]
  • Activity of Daily Living (ADL) [ Time Frame: 42 days ]
  • Plasmatic amino acid levels [ Time Frame: 42 days ]


Original Secondary Outcome:

  • Immune functions at 42 days
  • Hand-grip strength at 42 days
  • Biological nutritional parameters at 42 days
  • Mortality and morbidity (infections and bedsores) at 42 days
  • Activity of Daily Living (ADL) at 42 days
  • Plasmatic amino acid levels


Information By: Assistance Publique - Hôpitaux de Paris

Dates:
Date Received: August 24, 2005
Date Started: November 2004
Date Completion:
Last Updated: November 20, 2007
Last Verified: November 2004