Clinical Trial: Comparison of Effects of Intravenous Midazolam and Ketamine on Emergence Agitation

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Comparison of Effects of Intravenous Midazolam and Ketamine on Emergence Agitation : a Randomized Controlled Trial

Brief Summary: Compare the effects of intravenous midazolam and ketamine on emergence agitation after sevoflurane anesthesia

Detailed Summary: Emergence agitation is self-limiting aggressive behavior that develops in the early period of awakening from anesthesia. A high level of preoperative anxiety is a risk factor for emergence agitation using Aono's four-point scale. Midazolam and ketamine was administered to the patients to decrease of preoperative anxiety. We aimed to compare the emergence agitation between midazolam group and ketamine group.
Sponsor: Inje University

Current Primary Outcome: Emergence Agitation [ Time Frame: During 30 minutes after extubation at post-anesthetic care unit, every 5 minutes ]

The primary endpoint is the incidence of postoperative emergence agitation that was defined as an Aono's four-point scale(AFPS) score of 3 or higher.


Original Primary Outcome: Emergence Agitation [ Time Frame: 30 minutes after extubation at post-anesthetic care unit ]

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Inje University

Dates:
Date Received: October 1, 2014
Date Started: January 2013
Date Completion:
Last Updated: October 9, 2014
Last Verified: October 2014