Clinical Trial: The Effect of Dexmedetomidine on Emergence Agitation in Children Undergoing a Surgery Under Desflurane Anesthesia

Study Status: Completed
Recruit Status: Unknown status
Study Type: Interventional

Official Title: The Effect of Dexmedetomidine on Emergence Agitation in Children Undergoing a Surgery Under Desflurane Anesthesia

Brief Summary: After genernal anesthesia using sevoflurane or desflurane, the investigators can observe many cases of agiation (over 80%) and despite of no report of long-term complication, agitation is a big issue in PACU for doctors and nurses. The investigators use dexmedetomidine for prevention of agiation of preschool aged children. The investigators expect single injection of dexmedetomidine lead to decrease postoperative agitation and pain without any complication like oculocardiac reflex requiring atopine for treatment.

Detailed Summary: There are four groups accoding to dosage of dexmedetomidine. Dexmedetomidine 0.25 microg.kg(-1),(group D0.25), dexmedetomidine 0.5 microg.kg(-1),(Group D0.5), dexmedetomidine 1 microg.kg(-1) (Group D 1) and normal saline(group P) is administered ivs. for 10mins when we are inducing each patient.
Sponsor: Seoul National University Hospital

Current Primary Outcome: Agitation score [ Time Frame: 30 mins after operation ]

Original Primary Outcome: Same as current

Current Secondary Outcome: Oculomotor reflex [ Time Frame: Intraoperative ]

Original Secondary Outcome: Same as current

Information By: Seoul National University Hospital

Dates:
Date Received: April 13, 2012
Date Started: January 2012
Date Completion: April 2013
Last Updated: April 13, 2012
Last Verified: April 2012