Clinical Trial: Studying Fentanyl in Patients With Cancer
Study Status: Terminated
Recruit Status: Terminated
Study Type: Observational
Official Title: Pharmacokinetics of Continuous Infusion Fentanyl in Cancer Patients
Brief Summary:
RATIONALE: Studying blood samples from cancer patients undergoing pain treatment in the laboratory may help doctors learn more about how pain drugs work in the body. It may also help doctors predict how patients will respond to treatment.
PURPOSE: This research study is looking at fentanyl in patients with cancer.
Detailed Summary:
OBJECTIVES:
- To describe the pharmacokinetics of prolonged intravenous infusions of fentanyl citrate in adult patients with cancer.
OUTLINE: Patients undergo blood sample collection before and after discontinuation of fentanyl citrate therapy (10 days total). Pharmacokinetic analysis is performed on the samples.
Sponsor: Sidney Kimmel Comprehensive Cancer Center
Current Primary Outcome: Pharmacokinetics of fentanyl citrate [ Time Frame: two baseline samples, serial samples obtained at 0,4,8,24,48,72,96,168,240 hrs after discontinuing fentanyl ]
Original Primary Outcome: Pharmacokinetics of fentanyl citrate
Current Secondary Outcome:
Original Secondary Outcome:
Information By: Sidney Kimmel Comprehensive Cancer Center
Dates:
Date Received: May 9, 2009
Date Started: October 2007
Date Completion:
Last Updated: April 16, 2013
Last Verified: April 2013
